2-Amino-4-bromophenol

Basic Information

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CAS Number

40925-68-6

Molecular Formula

C6H6BrNO

Molecular Weight

188.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Yellow to Brown Solid

Melting Point

130-135 °C

Boiling Point

282.8℃ at 760 mmHg

Density

1.768

Flash Point

124.9℃

Refractive Index

1.677

SMILES

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C1=CC(=C(C=C1Br)N)O

InChI

InChI=1S/C6H6BrNO/c7-4-1-2-6(9)5(8)3-4/h1-3,9H,8H2

InChIKey

JHRIPENGTGSNPJ-UHFFFAOYSA-N

LogP

1.7368999999999999

Topological Polar Surface Area

46.25 Å²

Hydrogen Bond Donor/Acceptor

3 / 2

Complexity

99.1

Safety Information

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GHS Hazard Pictograms

H302

H315

H317

H319

H334

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

MFCD00235171
SY013005
MB01067
NSC523846
J-507836
AKOS005206940
SCHEMBL282322
BCP9000087
BCP22857
Phenol, 2-amino-4-bromo-
PS-4841
2-AMINO4-BROMOPHENOL
40925-68-6
CS-W007625
EN300-70638
AC-1070
2-amino-4bromophenol
Z385458142
2-Amino-4-bromophenol, >=98.0% (HPLC)
NSC-523846
2-Amino-4-bromophenol, >=94%
2-amino-4-bromo-phenol
2-Amino-4-Bromophenol
4-BROMO-2-AMINOPHENOL
DTXSID00326075
AM20060370
FT-0602128
5-Bromo-2-hydroxyaniline
CCG-326086
STR08168
A6818

MDL Number

MFCD00235171

Customs Code

2922299090

FAQ

What are the physical and chemical properties of 2-Amino-4-bromophenol (CAS: 40925-68-6)?

2-Amino-4-bromophenol (CAS: 40925-68-6) is a white to off-white crystalline solid with a molecular weight of approximately 228.02 g/mol. It is sparingly soluble in water but more soluble in organic solvents like ethanol and acetone. It exhibits basic properties due to the amino group and can undergo reactions typical for phenolic compounds, such as electrophilic aromatic substitution and nucleophilic substitution.

How is 2-Amino-4-bromophenol (CAS: 40925-68-6) typically synthesized?

2-Amino-4-bromophenol (CAS: 40925-68-6) is typically synthesized through the halogenation of 4-aminophenol using bromine in the presence of a base like sodium hydroxide. This reaction is conducted in an aqueous medium, and the product is isolated by filtration and recrystallization. The yield and purity can be improved by optimizing the reaction conditions and using appropriate purification techniques.

What industries use 2-Amino-4-bromophenol (CAS: 40925-68-6)?

2-Amino-4-bromophenol (CAS: 40925-68-6) is used in various industries. It is employed in pharmaceuticals for the synthesis of certain drug intermediates, in the polymer industry for the modification of polymer properties, in sensor technology for developing chemical sensors, and in semiconductor manufacturing for use as a dopant in certain materials.

What precautions should be taken when handling 2-Amino-4-bromophenol (CAS: 40925-68-6)?

When handling 2-Amino-4-bromophenol (CAS: 40925-68-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation of vapors. Spills should be cleaned up using absorbent materials, and the area should be thoroughly washed with water. Always consult the Material Safety Data Sheet (MSDS) for specific safety guidelines and emergency procedures.