Compound Q&A
How is tert-Butyl (5-bromo-6-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate (CAS: 1315351-28-0) typically synthesized?
Answer
This compound is synthesized via a Suzuki coupling reaction between 5-bromo-6-methylpyridin-2-ylamine and 4,4,5,5-tetramethyl-2-[(tert-butoxy)carbonyl]-1,3,2-dioxaborolane, using a palladium catalyst and a suitable base. The reaction typically yields a pure product with high selectivity and good yield.
About
CAS No
1315351-28-0
English Name
tert-Butyl (5-bromo-6-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate
Molecular Formula
C17H26BBrN2O4
Molecular Weight
413.1210000000001 g/mol
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC(=C(N=C2NC(=O)OC(C)(C)C)C)Br
InChIKey
LROLIRRLJWPKIL-UHFFFAOYSA-N
Last Updated: 2026-04-02 10:24
