Compound Q&A
How is Methyl 3-hydroxy-5-iodobenzoate (CAS: 50765-22-5) typically synthesized?
Answer
Methyl 3-hydroxy-5-iodobenzoate can be synthesized through the reaction of methyl 3-hydroxybenzoate with iodine in the presence of a suitable base, such as potassium carbonate, followed by recrystallization. The reaction is typically carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is around 70-80%.
About
CAS No
50765-22-5
English Name
Methyl 3-hydroxy-5-iodobenzoate
Molecular Formula
C8H7IO3
Molecular Weight
278.04499999999996 g/mol
SMILES
O=C(OC)C1=CC(I)=CC(O)=C1
InChIKey
PAVBUMACMQHDPH-UHFFFAOYSA-N
Last Updated: 2026-04-01 19:31
