Compound Q&A

How is N-Methoxy-N-methylpicolinamide (CAS: 148493-07-6) typically synthesized?

Answer

N-Methoxy-N-methylpicolinamide
N-Methoxy-N-methylpicolinamide is typically synthesized by the condensation of picolinic acid with methanol in the presence of a suitable base, such as sodium hydroxide, followed by the methylation of the resulting methoxypicolinamide with dimethyl sulfate. The reaction is carried out under mild conditions to achieve high selectivity and yield.

About

English Name N-Methoxy-N-methylpicolinamide
Molecular Formula C8H10N2O2
Molecular Weight 166.17999999999998 g/mol
SMILES CN(C(=O)C1=CC=CC=N1)OC
InChIKey JDRKBLOKFWKWKA-UHFFFAOYSA-N
Last Updated: 2026-04-01 19:31

Related Q&A

Compound Q&A

What are the physical and chemical properties of N-Methoxy-N-methylpicolinamide (CAS: 148493-07-6)?

N-Methoxy-N-methylpicolinamide (CAS: 148493-07-6) is a crystalline white powder. Its molecular weigh...

Compound Q&A

What industries use N-Methoxy-N-methylpicolinamide (CAS: 148493-07-6)?

N-Methoxy-N-methylpicolinamide (CAS: 148493-07-6) is primarily used in the pharmaceutical industry f...

Compound Q&A

What precautions should be taken when handling N-Methoxy-N-methylpicolinamide (CAS: 148493-07-6)?

When handling N-Methoxy-N-methylpicolinamide (CAS: 148493-07-6), it is essential to wear appropriate...

Compound Q&A

What precautions should be taken when handling 2-Chloro-1,2-bis(4-methylphenyl)ethanone (CAS: 71193-32-3)?

When handling 2-Chloro-1,2-bis(4-methylphenyl)ethanone (CAS: 71193-32-3), it is ...

71193-32-32-Chloro-1,2-bis(4-m...
Compound Q&A

What industries use 4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonyl chloride (CAS: 224789-26-8)?

4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl...

224789-26-84-Ethoxy-3-(5-methyl...
Compound Q&A

How should Methyl 3-Oxo-4-Androsten-17-Carboxylate (CAS: 2681-55-2) be stored?

Methyl 3-Oxo-4-Androsten-17-Carboxylate (CAS: 2681-55-2) should be stored in a c...

2681-55-2Methyl 3-Oxo-4-Andro...
Compound Q&A

What are the main uses of (R)-3-Amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid (CAS: 909725-61-7)?

(R)-3-Amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid is primarily used i...

909725-61-7(R)-3-Amino-4-(3-hex...