Compound Q&A
How is 5-Methyl-4-phenyl-2-pyrrolidinone (CAS: 50901-80-9) typically synthesized?
Answer
5-Methyl-4-phenyl-2-pyrrolidinone can be synthesized via the condensation of 4-phenylpyrrolidine with methyl acetoacetate. Commonly, this process involves the use of a base like sodium hydroxide as a catalyst. The yield is generally around 80-85%, and the reaction is conducted at room temperature under anhydrous conditions to enhance selectivity and yield.
About
CAS No
50901-80-9
English Name
5-Methyl-4-phenyl-2-pyrrolidinone
Molecular Formula
C11H13NO
Molecular Weight
175.231 g/mol
SMILES
O=C1NC(C)C(C2=CC=CC=C2)C1
InChIKey
ZIZRQVWVGIHEIC-UHFFFAOYSA-N
Last Updated: 2026-04-01 14:15
