Compound Q&A
How is N-Acetyl-L-leucyl-N-{(2S)-5-[(diaminomethylene)amino]-1-oxo-2-pentanyl}-L-leucinamide (CAS: 55123-66-5) typically synthesized?
Answer
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N-Acetyl-L-leucyl-N-{(2S)-5-[(diaminomethylene)amino]-1-oxo-2-pentanyl}-L-leucinamide (CAS: 55123-66-5) is synthesized through a multi-step process involving the condensation of L-leucine and a protected diamine derivative. The reaction typically requires the use of a coupling agent like EDC (N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide) and a base like DIPEA (N,N-Diisopropylethylamine). The yield is around 75-80%, and the product is purified by recrystallization from ethanol.
About
CAS No
55123-66-5
English Name
N-Acetyl-L-leucyl-N-{(2S)-5-[(diaminomethylene)amino]-1-oxo-2-pentanyl}-L-leucinamide
Molecular Formula
C20H38N6O4
Molecular Weight
951.2029999999995 g/mol
SMILES
CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C
InChIKey
GDBQQVLCIARPGH-ULQDDVLXSA-N
Last Updated: 2026-04-01 08:55
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