Compound Q&A

How is (1R)-1-(3-{[3-(2-{2-[({[1-(Chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy}acetyl)amino]ethoxy}ethoxy)propanoyl]amino}phenyl)-3-(3,4-dimethoxyphenyl)propyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)-2-piperidinecarboxylate (CAS: 2384184-40-9) typically synthesized?

Answer

(1R)-1-(3-{[3-(2-{2-[({[1-(Chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy}acetyl)amino]ethoxy}ethoxy)propanoyl]amino}phenyl)-3-(3,4-dimethoxyphenyl)propyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)-2-pip
eridinecarboxylate
The compound is typically synthesized via multi-step organic synthesis, involving protection and deprotection strategies, coupling reactions, and esterification. The reaction conditions include the use of catalysts such as HATU and DMAP, and the synthesis yields are around 50-60%. The key steps involve the introduction of various functional groups and their controlled modifications.

About

English Name (1R)-1-(3-{[3-(2-{2-[({[1-(Chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy}acetyl)amino]ethoxy}ethoxy)propanoyl]amino}phenyl)-3-(3,4-dimethoxyphenyl)propyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)-2-pip eridinecarboxylate
Molecular Formula C50H65ClN4O12
Molecular Weight 949.5389999999993 g/mol
SMILES CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCC1C=C(OC)C(=CC=1)OC)C1=CC(=CC=C1)NC(=O)CCOCCOCCNC(=O)COC1C=C2CCCN(C2=CC=1)C(=O)CCl
InChIKey OKJBKEQXKMMRPL-WVILEFPPSA-N
Last Updated: 2026-04-01 08:55

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