Compound Q&A
How is rac-(3R,4S)-4-methyloxolan-3-ol, trans (CAS: 387357-58-6) typically synthesized?
Answer
Rac-(3R,4S)-4-methyloxolan-3-ol, trans can be synthesized through the kinetic resolution of 1,4-dimethyl-2,3-epoxybutane using chiral auxiliaries. Common methods include the use of chiral metal complexes as catalysts, which provide good yields and high enantiomeric excess. The reaction typically involves the selective epimerization of one stereocenter, leading to the formation of the desired trans isomer.
About
CAS No
387357-58-6
English Name
rac-(3R,4S)-4-methyloxolan-3-ol, trans
Molecular Formula
C5H10O2
Molecular Weight
102.1317 g/mol
SMILES
C[C@@H]1COC[C@H]1O |&1:1,5,r|
InChIKey
FYIORKUEZVVKEL-WHFBIAKZSA-N
Last Updated: 2026-03-29 12:16
