Compound Q&A

How is 2-(1,3-Dioxolan-2-yl)-1,3-thiazole (CAS: 24295-04-3) typically synthesized?

Answer

2-(1,3-Dioxolan-2-yl)-1,3-thiazole
2-(1,3-Dioxolan-2-yl)-1,3-thiazole is usually synthesized by the condensation of 1,3-thiazole-2-carbaldehyde with 1,3-dioxane. The reaction is catalyzed by amines and occurs under mild conditions with high selectivity and yield. Commonly used solvents include methanol or acetic acid.

About

CAS No 24295-04-3
English Name 2-(1,3-Dioxolan-2-yl)-1,3-thiazole
Molecular Formula C6H7NO2S
Molecular Weight 157.194 g/mol
SMILES C1COC(O1)c2nccs2
InChIKey OIRJZETZODTGOD-UHFFFAOYSA-N
Last Updated: 2026-03-23 08:16

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