Compound Q&A

How is 5-(4-Pyridinyl)-1,3-oxazol-2-amine (CAS: 1014629-83-4) typically synthesized?

Answer

5-(4-Pyridinyl)-1,3-oxazol-2-amine
5-(4-Pyridinyl)-1,3-oxazol-2-amine can be synthesized via the condensation of 4-pyridylamine with oxirane, followed by hydrolysis of the resulting cyclic intermediate. This method provides good yield and selectivity, with the use of a mild base like potassium carbonate to facilitate the reaction.

About

English Name 5-(4-Pyridinyl)-1,3-oxazol-2-amine
Molecular Formula C8H7N3O
Molecular Weight 161.164 g/mol
SMILES Nc1ncc(o1)c1ccncc1
InChIKey DCRRIUJIVYWYRZ-UHFFFAOYSA-N
Last Updated: 2026-03-23 08:16

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