How is N-[(1Z)-1-(2-Bromophenyl)-1-chloro-3-oxo-3-(1-piperidinyl)-1-propen-2-yl]benzamide (CAS: 1800044-77-2) typically synthesized?

N-[(1Z)-1-(2-Bromophenyl)-1-chloro-3-oxo-3-(1-piperidinyl)-1-propen-2-yl]benzamide can be synthesized via a multi-step process involving the reaction of 2-bromophenylacetic acid with piperidine followed by acylation and amidation. The synthesis typically requires the use of reagents like piperidine, acetic anhydride, and a coupling agent such as 1-hydroxybenzotriazole. The yield is generally good, with high selectivity for the desired product.