Compound Q&A

How is 1-(4-thio-beta-D-ribofuranosyl)uracil (CAS: 6741-73-7) typically synthesized?

Answer

1-(4-thio-beta-D-ribofuranosyl)uracil
1-(4-Thio-beta-D-ribofuranosyl)uracil is typically synthesized via the condensation of 4-thio-ribofuranone with uracil. This reaction is catalyzed by a base such as triethylamine and proceeds with high selectivity. The yield is generally around 70-80%, and the product can be purified by recrystallization from ethanol.

About

CAS No 6741-73-7
English Name 1-(4-thio-beta-D-ribofuranosyl)uracil
Molecular Formula C9H12N2O5S
Molecular Weight 260.271 g/mol
SMILES C1=CN(C(=O)NC1=O)C2C(C(C(S2)CO)O)O
InChIKey MUSPKJVFRAYWAR-XVFCMESISA-N
Last Updated: 2026-03-19 14:17

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