Compound Q&A

How is 4-(4-(Trifluoromethyl)phenyl)oxazole (CAS: 1126636-40-5) typically synthesized?

Answer

4-(4-(Trifluoromethyl)phenyl)oxazole
4-(4-(Trifluoromethyl)phenyl)oxazole is commonly synthesized through a two-step process involving the reaction of 4-(trifluoromethyl)benzoyl chloride with hydroxylamine hydrochloride. This method provides good selectivity and yield. The reaction is typically carried out in an inert solvent such as dichloromethane under mild conditions.

About

English Name 4-(4-(Trifluoromethyl)phenyl)oxazole
Molecular Formula C10H6F3NO
Molecular Weight 213.15799999999996 g/mol
SMILES C1=CC(=CC=C1C2=COC=N2)C(F)(F)F
InChIKey BTZWCQXESYHHBK-UHFFFAOYSA-N
Last Updated: 2026-03-17 15:30

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