Compound Q&A

How is 6-Bromofuro[3,2-b]pyridine-2-carbonitrile (CAS: 1203498-94-5) typically synthesized?

Answer

6-Bromofuro[3,2-b]pyridine-2-carbonitrile
6-Bromofuro[3,2-b]pyridine-2-carbonitrile is commonly synthesized via the bromination of furo[3,2-b]pyridine followed by a nucleophilic substitution with carbonitrile. The reaction typically involves the use of N-bromosuccinimide (NBS) as a brominating agent and is conducted in an inert atmosphere to avoid side reactions. The product shows good yield and selectivity under these conditions.

About

English Name 6-Bromofuro[3,2-b]pyridine-2-carbonitrile
Molecular Formula C8H3BrN2O
Molecular Weight 17.031 g/mol
SMILES C1=C(C=NC2=C1OC(=C2)C#N)Br
InChIKey DCCFLNQLIYYNHQ-UHFFFAOYSA-N
Last Updated: 2026-03-17 06:03

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