Compound Q&A

How is 2-Methyl-2-propanyl [(3S,4R)-4-fluoro-3-pyrrolidinyl]carbamate (CAS: 1033718-89-6) typically synthesized?

Answer

2-Methyl-2-propanyl [(3S,4R)-4-fluoro-3-pyrrolidinyl]carbamate
This compound can be synthesized via a multi-step process involving the protection of an amine, introduction of the fluorine substituent, and subsequent carbamoylation. Commonly used reagents include fluoroacetic acid and a suitable carbonylating agent like carbonyldiimidazole. The reaction proceeds with good selectivity and yields up to 85% depending on the specific method employed.

About

English Name 2-Methyl-2-propanyl [(3S,4R)-4-fluoro-3-pyrrolidinyl]carbamate
Molecular Formula C9H17FN2O2
Molecular Weight 204.24499999999998 g/mol
SMILES F[C@@H]1CNC[C@@H]1NC(=O)OC(C)(C)C
InChIKey BZSDDSIFAGBZLT-RQJHMYQMSA-N
Last Updated: 2026-03-17 01:51

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