Compound Q&A

How is 2-(4-Fluorobenzyl)pyrrolidine (CAS: 350017-04-8) typically synthesized?

Answer

2-(4-Fluorobenzyl)pyrrolidine
2-(4-Fluorobenzyl)pyrrolidine is typically synthesized via a multistep process involving the coupling reaction between 4-fluorobenzyl bromide and pyrrolidine in the presence of a base like sodium hydride. The reaction is usually carried out in a solvent such as dimethylformamide (DMF) or N,N-dimethylacetamide (DMA). The product can be isolated by extraction and recrystallization from appropriate solvents.

About

English Name 2-(4-Fluorobenzyl)pyrrolidine
Molecular Formula C11H14FN
Molecular Weight 179.23800000000003 g/mol
SMILES C1CC(NC1)CC2=CC=C(C=C2)F
InChIKey VVKUNLLPKQCGHF-UHFFFAOYSA-N
Last Updated: 2026-03-10 19:33

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