Compound Q&A

How is 5β-Dihydrocortisol (CAS: 1482-50-4) typically synthesized?

Answer

5β-Dihydrocortisol
5β-Dihydrocortisol (CAS: 1482-50-4) is synthesized through a series of enzymatic and chemical reactions. Typically, it involves the demethylation of cortisol at the 11β position followed by reduction at the 5β position. Commonly used catalysts include hydrogenation in the presence of palladium on carbon. The synthetic route provides good yield and selectivity.

About

CAS No 1482-50-4
English Name 5β-Dihydrocortisol
Molecular Formula C21H32O5
Molecular Weight 364.5 g/mol
SMILES CC12CCC(=O)CC1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O
InChIKey ACSFOIGNUQUIGE-AIPUTVCKSA-N
Last Updated: 2026-03-10 19:33

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