Compound Q&A

How is (2R,5R)-2,5-Dimethylpyrrolidine hydrochloride (CAS: 70144-18-2) typically synthesized?

Answer

(2R,5R)-2,5-Dimethylpyrrolidine hydrochloride (1:1)

(2R,5R)-2,5-Dimethylpyrrolidine hydrochloride is usually synthesized through the oxidative cyclization of 2,5-dimethylpyrrolidine in the presence of a catalytic amount of an oxidant such as potassium permanganate or sodium hypochlorite. The reaction yields a high yield of the desired hydrochloride salt.

About

CAS No 70144-18-2

English Name (2R,5R)-2,5-Dimethylpyrrolidine hydrochloride (1:1)

Molecular Formula C6H14ClN

Molecular Weight 135.638 g/mol

SMILES CC1CCC(N1)C.Cl

InChIKey AFHNFHHYTYQLIO-KGZKBUQUSA-N

Last Updated: 2026-03-05 12:33

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How is (2R,5R)-2,5-Dimethylpyrrolidine hydrochloride (CAS: 70144-18-2) typically synthesized?

Answer

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