How is (3E)-4-[(3R,4S)-3,4-Dihydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl]-3-buten-2-one (CAS: 875666-39-0) typically synthesized?

This compound can be synthesized using a multistep process involving the formation of the cyclic alcohol intermediate followed by the introduction of the alkenyl group. Common synthetic routes involve the use of chiral catalysts to achieve enantioselectivity. Typical yields range from 50% to 70%, and the reaction is conducted under mild conditions to preserve the chiral centers.