Compound Q&A
How is (5alpha)-17-(Cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6,10-dione (CAS: 96445-14-6) typically synthesized?
Answer
(5alpha)-17-(Cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6,10-dione is synthesized through a multistep process involving epoxidation of a morphinan derivative, followed by dihydroxylation and cyclopropylation. Common catalysts include platinum-based complexes, yielding up to 90% purity with excellent selectivity. The reaction is conducted under an inert atmosphere to prevent degradation.
About
CAS No
96445-14-6
English Name
(5alpha)-17-(Cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6,10-dione
Molecular Formula
C20H21NO5
Molecular Weight
355.39000000000004 g/mol
SMILES
c1cc(c2c3c1C(=O)[C@@H]4[C@]5([C@]3(CCN4CC6CC6)[C@@H](O2)C(=O)CC5)O)O
InChIKey
MLHMRULRADVYER-FUMNGEBKSA-N
Last Updated: 2026-03-04 21:36
