How is 5-Bromo-2-(methylsulfinyl)pyrimidine (CAS: 79685-17-9) typically synthesized?

5-Bromo-2-(methylsulfinyl)pyrimidine is typically synthesized by bromination of 2-(methylthio)pyrimidine followed by oxidation of the sulfhydryl group to a sulfoxide. The reaction is usually carried out using N-bromosuccinimide (NBS) as the brominating agent and a radical initiator. The yield is generally high, and the selectivity is good, making it a suitable method for producing this compound.