Compound Q&A
How is (1R,2S,5S)-methyl 6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate (2S,3S)-2,3-bis(4-methylbenzoyloxy)succinate (CAS: 943516-64-1) typically synthesized?
Answer
![(1R,2S,5S)-methyl 6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate (2S,3S)-2,3-bis(4-methylbenzoyloxy)succinate](https://static.chemtradehub.com/structs/943/943516-64-1-f7a0.webp "(1R,2S,5S)-methyl 6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate (2S,3S)-2,3-bis(4-methylbenzoyloxy)succinate")
This compound is commonly synthesized via a multi-step process involving the condensation of methyl 6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate with 2,3-bis(4-methylbenzoyloxy)succinic anhydride. The reaction is typically carried out under anhydrous conditions, often using a catalytic amount of a Lewis acid to enhance the reaction's yield and selectivity.
About
CAS No
943516-64-1
English Name
(1R,2S,5S)-methyl 6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate (2S,3S)-2,3-bis(4-methylbenzoyloxy)succinate
Molecular Formula
C38H44N2O12
Molecular Weight
720.772 g/mol
SMILES
CC1=CC=C(C=C1)C(=O)OC(C(C(=O)O)OC(=O)C2=CC=C(C=C2)C)C(=O)O.CC1(C2C1C(NC2)C(=O)OC)C
InChIKey
YZFGAUDVWYMIOU-QLGHABEQSA-N
Last Updated: 2026-03-04 16:30
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