Compound Q&A

How is 2-Chloro-6-cyclopropylpyrazine (CAS: 1209457-99-7) typically synthesized?

Answer

2-Chloro-6-cyclopropylpyrazine
2-Chloro-6-cyclopropylpyrazine can be synthesized by the direct condensation of 2-chloro-6-cyclopropylpyrazine-3-carbaldehyde with an appropriate nucleophile, such as an amine, in the presence of a suitable base like sodium hydroxide. The reaction is carried out at elevated temperatures to achieve good yield and selectivity.

About

English Name 2-Chloro-6-cyclopropylpyrazine
Molecular Formula C7H7ClN2
Molecular Weight 154.59999999999997 g/mol
SMILES C1CC1C2=CN=CC(=N2)Cl
InChIKey AYKSCRVEBJUBTR-UHFFFAOYSA-N
Last Updated: 2026-01-13 15:28

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