Compound Q&A
How is 3-(4-Fluorophenoxy)propanenitrile (CAS: 85169-02-4) typically synthesized?
Answer
3-(4-Fluorophenoxy)propanenitrile is typically synthesized by the reaction of 4-fluorophenol with propionitrile in the presence of a base such as sodium hydride. The reaction is conducted in a solvent like dimethylformamide (DMF) under anhydrous conditions. The yield is around 90% and the method is known for its high selectivity and good reproducibility.
About
CAS No
85169-02-4
English Name
3-(4-Fluorophenoxy)propanenitrile
Molecular Formula
C9H8FNO
Molecular Weight
165.16 g/mol
SMILES
C1=CC(=CC=C1OCCC#N)F
InChIKey
MSQBUHCLFYFIGC-UHFFFAOYSA-N
Last Updated: 2026-01-13 15:28
