Compound Q&A
How is (2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol (CAS: 26839-75-8) typically synthesized?
Answer
![(2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol](https://static.chemtradehub.com/structs/268/26839-75-8-f247.webp "(2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol")
(2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol can be synthesized via a multi-step process involving reaction of tert-butylamine with 4-(morpholin-4-yl)-1,2,5-thiadiazole followed by coupling with propan-2-ol. The reaction is typically carried out in an aqueous solvent with a catalyst such as sodium hydride. The yield is moderate, around 50-60%, and the product is purified by column chromatography or recrystallization.
About
CAS No
26839-75-8
English Name
(2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol
Molecular Formula
C13H24N4O3S
Molecular Weight
316.4270000000002 g/mol
SMILES
CC(C)(C)NCC(COC1=NSN=C1N2CCOCC2)O
InChIKey
BLJRIMJGRPQVNF-JTQLQIEISA-N
Last Updated: 2026-01-13 06:11