Compound Q&A

How is 8-bromo-2,2-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-3-one (CAS: 688363-73-7) typically synthesized?

Answer

8-bromo-2,2-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-3-one
8-bromo-2,2-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-3-one is commonly synthesized via bromination of 2,2-dimethyl-3,4-dihydro-2H-1,4-benzoxazine-3-one, followed by a coupling reaction. The synthesis involves the use of bromine in the presence of an appropriate base and solvent. High selectivity and good yield are observed.

About

English Name 8-bromo-2,2-dimethyl-3,4-dihydro-2H-1,4-benzoxazin-3-one
Molecular Formula C10H10BrNO2
Molecular Weight 256.09900000000005 g/mol
SMILES CC1(C(=O)NC2=C(O1)C(=CC=C2)Br)C
InChIKey ZYPVSNYNICRCNG-UHFFFAOYSA-N
Last Updated: 2026-01-07 10:17

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