Compound Q&A

How is 3-(4-Chlorophenyl)-3-oxetanamine hydrochloride (CAS: 1245782-61-9) typically synthesized?

Answer

3-(4-Chlorophenyl)-3-oxetanamine hydrochloride (1:1)
3-(4-Chlorophenyl)-3-oxetanamine hydrochloride is typically synthesized by the condensation of 4-chlorophenyl isocyanate with 3-oxetanamine in the presence of a catalytic amount of a Lewis acid such as aluminum chloride. The reaction is carried out in an inert solvent like dichloromethane. The product is obtained with good yield and high selectivity.

About

English Name 3-(4-Chlorophenyl)-3-oxetanamine hydrochloride (1:1)
Molecular Formula C9H11Cl2NO
Molecular Weight 220.09900000000002 g/mol
SMILES Cl.NC1(COC1)c2ccc(Cl)cc2
InChIKey DNVPDMXUPGYAPY-UHFFFAOYSA-N
Last Updated: 2026-01-07 05:52

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