Compound Q&A

How is 4-(Pyrrolidin-1-yl)cyclohexanone (CAS: 10421-18-8) typically synthesized?

Answer

4-(Pyrrolidin-1-yl)cyclohexanone
4-(Pyrrolidin-1-yl)cyclohexanone (CAS: 10421-18-8) can be synthesized by reacting cyclohexanone with pyrrolidine in an organic solvent such as ethanol or acetonitrile in the presence of a suitable catalyst like potassium hydroxide. The reaction is typically carried out at room temperature, and the product can be isolated by recrystallization from appropriate solvents. The yield is generally around 70-80%, depending on the purity of starting materials and reaction conditions.

About

CAS No 10421-18-8
English Name 4-(Pyrrolidin-1-yl)cyclohexanone
Molecular Formula C10H17NO
Molecular Weight 167.25199999999998 g/mol
SMILES C1CCN(C1)C2CCC(=O)CC2
InChIKey RDGIABKZGSKWCC-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14

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