Compound Q&A

How is 1-(3-Fluoro-2-pyridinyl)ethanol (CAS: 87674-14-4) typically synthesized?

Answer

1-(3-Fluoro-2-pyridinyl)ethanol
1-(3-Fluoro-2-pyridinyl)ethanol (CAS: 87674-14-4) can be synthesized by reacting 3-fluoro-2-pyridinecarbaldehyde with ethanol in the presence of a base such as sodium hydroxide. The reaction is typically conducted in an aprotic solvent like dimethylformamide (DMF). The yield is generally around 80%, and the reaction is selective and efficient under these conditions.

About

CAS No 87674-14-4
English Name 1-(3-Fluoro-2-pyridinyl)ethanol
Molecular Formula C7H8FNO
Molecular Weight 141.14499999999998 g/mol
SMILES CC(C1=C(C=CC=N1)F)O
InChIKey VWXJHLSFAQVXJE-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14

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