Compound Q&A

Are there alternatives to N,N-Bis(2-chloroethyl)phosphorodiamidic acid - cyclohexanamine (CAS: 1566-15-0) in synthesis?

Answer

N,N-Bis(2-chloroethyl)phosphorodiamidic acid - cyclohexanamine (1:1)
Alternatives to N,N-Bis(2-chloroethyl)phosphorodiamidic acid - cyclohexanamine include other phosphoramidites and related compounds. Common substitutes include N,N-Dimethylaminopropyl carbodiimide (DMAP) or 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC), which are often used in similar synthetic applications, although they may have different reactivity profiles.

About

CAS No 1566-15-0
English Name N,N-Bis(2-chloroethyl)phosphorodiamidic acid - cyclohexanamine (1:1)
Molecular Formula C10H24Cl2N3O2P
Molecular Weight 320.2010000000001 g/mol
SMILES C1CCC(CC1)N.C(CCl)N(CCCl)P(=O)(N)O
InChIKey BGTIPRUDEMNRIP-UHFFFAOYSA-N
Last Updated: 2026-01-02 07:09

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