Compound Q&A
How is (1S)-1-(2-methoxyphenyl)propan-1-amine hydrochloride (CAS: 873893-95-9) typically synthesized?
Answer
Synthesis of (1S)-1-(2-methoxyphenyl)propan-1-amine hydrochloride typically involves the reaction of 2-methoxyphenylglycine with hydrochloric acid. The reaction is usually conducted in a polar aprotic solvent such as dimethylformamide (DMF) under reflux conditions. The yield is around 80-85%, and the product is isolated by recrystallization from a suitable solvent. The reaction is selective and provides good purity.
About
CAS No
873893-95-9
English Name
(1S)-1-(2-methoxyphenyl)propan-1-amine;hydrochloride
Molecular Formula
C10H16ClNO
Molecular Weight
201.69 g/mol
SMILES
CCC(C1=CC=CC=C1OC)N.Cl
InChIKey
XPWHPGHAPKCHQY-FVGYRXGTSA-N
Last Updated: 2026-01-02 00:31
