Compound Q&A

How is (7S,15R)-6β,15-Diacetoxy-7α,20-epoxy-7-hydroxykaura-2,16-dien-1-one (CAS: 51419-51-3) typically synthesized?

Answer

(7S,15R)-6β,15-Diacetoxy-7α,20-epoxy-7-hydroxykaura-2,16-dien-1-one
(7S,15R)-6β,15-Diacetoxy-7α,20-epoxy-7-hydroxykaura-2,16-dien-1-one is synthesized through a multi-step procedure involving acetylation, epoxidation, and dihydroxylation reactions. Commonly, the synthesis is carried out using catalytic amounts of acetic anhydride as the acetylation reagent, and m-chloroperoxybenzoic acid (MCPBA) for epoxidation. The overall yield is around 70%, and the process is optimized to achieve high selectivity.

About

CAS No 51419-51-3
English Name (7S,15R)-6β,15-Diacetoxy-7α,20-epoxy-7-hydroxykaura-2,16-dien-1-one
Molecular Formula C24H30O7
Molecular Weight 430.5 g/mol
SMILES CC(=O)OC1C2C(C=CC(=O)C23COC1(C45C3CCC(C4)C(=C)C5OC(=O)C)O)(C)C
InChIKey VIZWMBLJPXPZSQ-CMJIRCKQSA-N
Last Updated: 2026-01-02 00:31

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