Compound Q&A

How is 5-Bromo-3-methyl-1-benzofuran-2-carboxylic acid (CAS: 50638-08-9) typically synthesized?

Answer

5-Bromo-3-methyl-1-benzofuran-2-carboxylic acid
5-Bromo-3-methyl-1-benzofuran-2-carboxylic acid is typically synthesized through the bromination of 3-methyl-1-benzofuran-2-carboxylic acid. The reaction involves the use of bromine in the presence of an appropriate base such as sodium hydride. The yield is usually high, and the reaction can be carried out in a solvent like THF or DMSO. Care should be taken to ensure selective bromination and to maintain the purity of the product.

About

CAS No 50638-08-9
English Name 5-Bromo-3-methyl-1-benzofuran-2-carboxylic acid
Molecular Formula C10H7BrO3
Molecular Weight 255.06699999999998 g/mol
SMILES Cc1c(oc2ccc(Br)cc12)C(=O)O
InChIKey XXPAQRBXERJCQH-UHFFFAOYSA-N
Last Updated: 2026-01-01 15:34

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