Compound Q&A
How is 5'-Bromospiro[cyclohexane-1,3'-indol]-2'(1'H)-one (CAS: 304468-42-6) typically synthesized?
Answer
![5'-Bromospiro[cyclohexane-1,3'-indol]-2'(1'H)-one](https://static.chemtradehub.com/structs/304/304468-42-6-a4bd.webp "5'-Bromospiro[cyclohexane-1,3'-indol]-2'(1'H)-one")
5'-Bromospiro[cyclohexane-1,3'-indol]-2'(1'H)-one is typically synthesized via a multi-step process involving the condensation of an indole derivative with a cyclohexane derivative, followed by bromination. The reaction is catalyzed by a Lewis acid, and the yield is around 50-60%.
About
CAS No
304468-42-6
English Name
5'-Bromospiro[cyclohexane-1,3'-indol]-2'(1'H)-one
Molecular Formula
C13H14BrNO
Molecular Weight
280.1649999999999 g/mol
SMILES
C1CCC2(CC1)C3=C(C=CC(=C3)Br)NC2=O
InChIKey
MOCOBMQLHAVEMT-UHFFFAOYSA-N
Last Updated: 2026-01-01 06:12
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