Compound Q&A

How is 4-(Dimethoxymethyl)-2-(trifluoromethyl)pyrimidine (CAS: 878760-47-5) typically synthesized?

Answer

4-(Dimethoxymethyl)-2-(trifluoromethyl)pyrimidine
4-(Dimethoxymethyl)-2-(trifluoromethyl)pyrimidine (CAS: 878760-47-5) is typically synthesized through a multistep process involving the protection of the pyrimidine ring followed by the installation of the trifluoromethyl group. Commonly used reagents include dimethylformamide (DMF) and trifluoromethyl triflate. The reaction is typically carried out under mild conditions, with high selectivity and good yield.

About

English Name 4-(Dimethoxymethyl)-2-(trifluoromethyl)pyrimidine
Molecular Formula C8H9F3N2O2
Molecular Weight 222.16599999999994 g/mol
SMILES FC(C1=NC=CC(C(OC)OC)=N1)(F)F
InChIKey CHSZUWDVGYPDPG-UHFFFAOYSA-N
Last Updated: 2026-01-01 01:49

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