Compound Q&A

How is 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (CAS: 153631-19-7) typically synthesized?

Answer

1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
This compound is prepared by a multi-step synthesis involving the protection of hydroxyl groups, formation of a methoxyphenyl derivative, and subsequent coupling reactions. The synthesis requires careful control of reagents and conditions to achieve high yield and selectivity. Common catalysts and reagents include triphenylphosphine and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU).

About

English Name 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
Molecular Formula C32H34N2O8
Molecular Weight 574.6300000000002 g/mol
SMILES CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OC
InChIKey VFLOXJCZWDDILQ-NODMTMHWSA-N
Last Updated: 2025-12-31 21:15

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