Compound Q&A

How is Methyl 2-(bromomethyl)-5-methoxybenzoate (CAS: 788081-99-2) typically synthesized?

Answer

Methyl 2-(bromomethyl)-5-methoxybenzoate
Methyl 2-(bromomethyl)-5-methoxybenzoate is typically synthesized by reacting methyl 5-methoxybenzoate with bromine in the presence of a base such as sodium hydroxide. The reaction is carried out in a solvent like chloroform or dichloromethane. The yield is moderate, and the reaction is selective towards the bromomethylation of the aromatic ring. This process is often performed under reflux conditions to ensure complete conversion.

About

English Name Methyl 2-(bromomethyl)-5-methoxybenzoate
Molecular Formula C10H11BrO3
Molecular Weight 259.099 g/mol
SMILES COC1=CC(=C(C=C1)CBr)C(=O)OC
InChIKey GQGYGEVWBRHRTD-UHFFFAOYSA-N
Last Updated: 2025-12-31 16:28

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