Compound Q&A
How is N-({(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide (CAS: 872992-20-6) typically synthesized?
Answer
![N-({(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide](https://static.chemtradehub.com/structs/872/872992-20-6-1f59.webp "N-({(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide")
This compound is typically synthesized via condensation of 3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl methyl ester with acetamide, under anhydrous conditions. It involves the use of a mild base like triethylamine and is carried out in an inert solvent like dichloromethane. The yield is usually around 75-80%.
About
CAS No
872992-20-6
English Name
N-({(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
Molecular Formula
C16H20FN3O4
Molecular Weight
337.3510000000001 g/mol
SMILES
CC(=O)NC[C@@H]1CN(C(=O)O1)c2ccc(N3CCOCC3)c(F)c2
InChIKey
TYZROVQLWOKYKF-CYBMUJFWSA-N
Last Updated: 2025-12-31 06:49
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