Compound Q&A

How is (1R)-1-(4-Methylphenyl)-1-propanamine (CAS: 239105-47-6) typically synthesized?

Answer

(1R)-1-(4-Methylphenyl)-1-propanamine
(1R)-1-(4-Methylphenyl)-1-propanamine can be synthesized via aminating 4-methylbenzyl chloride with ammonia in the presence of an acid catalyst such as hydrochloric acid. The reaction is performed at room temperature, and the product is isolated by distillation. Yield and selectivity can be enhanced by optimizing reaction conditions.

About

English Name (1R)-1-(4-Methylphenyl)-1-propanamine
Molecular Formula C10H15N
Molecular Weight 149.23699999999997 g/mol
SMILES N[C@@H](c1ccc(cc1)C)CC
InChIKey FWTZOQCAVLMPJE-SNVBAGLBSA-N
Last Updated: 2025-12-29 01:16

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