Compound Q&A

How is 4-(1H-Pyrazol-3-yl)piperidine (CAS: 278798-08-6) typically synthesized?

Answer

4-(1H-Pyrazol-3-yl)piperidine
4-(1H-Pyrazol-3-yl)piperidine (CAS: 278798-08-6) is synthesized via condensation of 3-amino-1H-pyrazole and piperidines in the presence of a suitable catalyst, such as triphenyl phosphine. The reaction typically involves refluxing the mixture under an atmosphere of nitrogen for several hours to achieve high yield and selectivity. Common solvents include DMF or DMSO.

About

English Name 4-(1H-Pyrazol-3-yl)piperidine
Molecular Formula C8H13N3
Molecular Weight 151.213 g/mol
SMILES C1CNCCC1C2=CC=NN2
InChIKey FCKYIGWJVZIPLK-UHFFFAOYSA-N
Last Updated: 2025-12-28 10:59

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