Compound Q&A

Are there alternatives to Sodium N-{[(2R,6S)-2,6-dimethyl-1-piperidinyl]carbonyl}-4-methyl-L-leucyl-N-[(1R)-1-carboxylatopentyl]-1-(methoxycarbonyl)-D-tryptophanamide (CAS: 156161-89-6) in synthesis?

Answer

Sodium N-{[(2R,6S)-2,6-dimethyl-1-piperidinyl]carbonyl}-4-methyl-L-leucyl-N-[(1R)-1-carboxylatopentyl]-1-(methoxycarbonyl)-D-tryptophanamide
Alternatives include using similar analogs or isomers such as related amino acids or piperidine derivatives. Common alternative reagents include other amide-forming agents like carbodiimides or coupling reagents like HATU. These alternatives can reduce cost and improve synthetic efficiency, but thorough testing is necessary to ensure equivalent efficacy and safety.

About

English Name Sodium N-{[(2R,6S)-2,6-dimethyl-1-piperidinyl]carbonyl}-4-methyl-L-leucyl-N-[(1R)-1-carboxylatopentyl]-1-(methoxycarbonyl)-D-tryptophanamide
Molecular Formula C34H50N5NaO7
Molecular Weight 663.8 g/mol
SMILES CCCCC(C(=O)[O-])NC(=O)C(CC1=CN(C2=CC=CC=C21)C(=O)OC)NC(=O)C(CC(C)(C)C)NC(=O)N3C(CCCC3C)C.[Na+]
InChIKey QCVIFBRTTLMEOV-FUKQNADPSA-M
Last Updated: 2025-12-26 17:17

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