Compound Q&A
How is N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide (CAS: 959151-50-9) typically synthesized?
Answer
N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide is usually synthesized through a multi-step process involving the condensation of 3-aminobenzaldehyde and 4-phenyl-1-piperidinyldiacetamide followed by quinoline coupling. This process typically uses catalytic amounts of a strong base and a coupling agent. The overall yield is around 70%, with good selectivity to the desired product.
About
CAS No
959151-50-9
English Name
N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide
Molecular Formula
C22H23N3O
Molecular Weight
345.44599999999997 g/mol
SMILES
C1CN(CCC1CC2=CC3=CC=CC=C3N=C2)C(=O)NC4=CC=CC=C4
InChIKey
BIODYGOZWZNCAG-UHFFFAOYSA-N
Last Updated: 2025-12-26 02:37
