Compound Q&A
How is 4-(4-{4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl}-1-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate (CAS: 1082949-68-5) typically synthesized?
Answer
![4-(4-{4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl}-1-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate (1:1)](https://static.chemtradehub.com/structs/108/1082949-68-5-00b6.webp "4-(4-{4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl}-1-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate (1:1)")
This compound is synthesized via a multi-step process involving the coupling of imidazole derivatives with piperidine and subsequent sulfonation. The reaction is typically carried out in the presence of a suitable base and a coupling agent. The yield is moderate, around 50-70%, with high selectivity for the desired product.
About
CAS No
1082949-68-5
English Name
4-(4-{4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl}-1-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate (1:1)
Molecular Formula
C28H27F4N7O3S
Molecular Weight
617.6290000000002 g/mol
SMILES
Cn1cc(nc1C1CCN(CC1)c1ncnc2c1cn[nH]2)c1ccc(c(c1)C(F)(F)F)F.Cc1ccc(cc1)S(=O)(=O)O
InChIKey
HDYUXDNMHBQKAU-UHFFFAOYSA-N
Last Updated: 2025-12-26 02:37
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