Compound Q&A
How is 8-Bromo-5-(trifluoromethyl)quinoline (CAS: 917251-92-4) typically synthesized?
Answer
8-Bromo-5-(trifluoromethyl)quinoline is synthesized through the bromination of 5-(trifluoromethyl)quinoline using N-bromosuccinimide (NBS) as the brominating agent. The reaction is carried out under UV light, and the product can be purified by recrystallization. This method provides high selectivity and yield.
About
CAS No
917251-92-4
English Name
8-Bromo-5-(trifluoromethyl)quinoline
Molecular Formula
C10H5BrF3N
Molecular Weight
276.055 g/mol
SMILES
C1=CC2=C(C=CC(=C2N=C1)Br)C(F)(F)F
InChIKey
SLRQZPDPELUOEM-UHFFFAOYSA-N
Last Updated: 2025-12-26 02:37
