How is Benzoic acid, 2-fluoro-4-iodo-, ethyl ester (CAS: 205750-82-9) typically synthesized?

Benzoic acid, 2-fluoro-4-iodo-, ethyl ester is typically synthesized through a multi-step process starting with benzoic acid. The acid is first iodinated using N-iodosuccinimide (NIS) and sodium hydroxide in an aqueous solution. Subsequently, the 4-iodo compound is esterified with ethyl alcohol in the presence of an acid catalyst such as sulfuric acid. This reaction yields the ethyl ester with high selectivity and good yield.