Compound Q&A

How is (E)-2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-ol (CAS: 581802-26-8) typically synthesized?

Answer

(E)-2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-ol
This compound can be synthesized via a Ring-Opening Metathesis Polymerization (ROMP) process involving the reaction of a boronic ester with an alkene. The synthesis typically requires a Grubbs-type catalyst and is performed in an inert atmosphere to prevent decomposition. The yield is generally high, and the purity can be enhanced through column chromatography.

About

English Name (E)-2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-2-ol
Molecular Formula C11H21BO3
Molecular Weight 212.09799999999996 g/mol
SMILES B1(OC(C(O1)(C)C)(C)C)C=CC(C)(C)O
InChIKey FBCZPBPTNCLUII-BQYQJAHWSA-N
Last Updated: 2025-12-25 13:43

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