Compound Q&A

How is 2',2,5 Trichloroacetophenone (CAS: 7396-79-4) typically synthesized?

Answer

2',2,5 Trichloroacetophenone
2',2,5 Trichloroacetophenone (CAS: 7396-79-4) can be synthesized via the chlorination of acetophenone using thionyl chloride or phosphorus trichloride as a chlorinating agent. The reaction is typically carried out under anhydrous conditions in a suitable solvent such as tetrahydrofuran (THF) or dichloromethane. The yield of the product can be enhanced by the use of a phase-transfer catalyst and appropriate reaction conditions.

About

CAS No 7396-79-4
English Name 2',2,5 Trichloroacetophenone
Molecular Formula C8H5Cl3O
Molecular Weight 223.486 g/mol
SMILES C1=CC(=C(C=C1Cl)C(=O)CCl)Cl
InChIKey CXEVBWANBXAQSY-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29

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