Compound Q&A

How is Methyl 1-((tert-butoxycarbonyl)amino)cyclopropanecarboxylate (CAS: 66494-26-6) typically synthesized?

Answer

Methyl 1-((tert-butoxycarbonyl)amino)cyclopropanecarboxylate
Methyl 1-((tert-butoxycarbonyl)amino)cyclopropanecarboxylate (CAS: 66494-26-6) is synthesized through a multi-step process involving the protection of an amino group with a tert-butoxycarbonyl (BOC) group. Commonly, this involves reacting cyclopropanecarboxylic acid with tert-butanol in the presence of a suitable coupling agent such as DCC (dicyclohexylcarbodiimide) and anhydrous pyridine. The yield and selectivity of this reaction are influenced by the conditions and choice of reagents.

About

CAS No 66494-26-6
English Name Methyl 1-((tert-butoxycarbonyl)amino)cyclopropanecarboxylate
Molecular Formula C10H17NO4
Molecular Weight 215.249 g/mol
SMILES CC(C)(C)OC(=O)NC1(CC1)C(=O)OC
InChIKey ACXGDYTVQAXJHI-UHFFFAOYSA-N
Last Updated: 2025-11-28 19:29

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