Compound Q&A

How is [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine (CAS: 132-22-9) typically synthesized?

Answer

[3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine
The compound [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine (CAS: 132-22-9) can be synthesized via a multi-step process involving alkylation of a pyridine derivative with a chlorophenyl propyl halide, followed by an amination step using dimethylamine. The reaction typically requires the use of a Lewis acid catalyst such as aluminum chloride and proceeds with good selectivity and yield. The final product can be isolated and purified by recrystallization.

About

CAS No 132-22-9
English Name [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine
Molecular Formula C16H19ClN2
Molecular Weight 274.795 g/mol
SMILES CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2
InChIKey SOYKEARSMXGVTM-UHFFFAOYSA-N
Last Updated: 2025-11-07 19:01

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