Compound Q&A
How is 1-[(Benzyloxy)carbonyl]-4-oxo-L-proline (CAS: 64187-47-9) typically synthesized?
Answer
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1-[(Benzyloxy)carbonyl]-4-oxo-L-proline can be synthesized via the condensation of benzyloxycarbonyl chloride with L-proline, followed by dehydration. Commonly, this reaction is performed in the presence of a base such as triethylamine. The overall yield is typically around 75-85%, and the reaction is selective for the desired product.
About
CAS No
64187-47-9
English Name
1-[(Benzyloxy)carbonyl]-4-oxo-L-proline
Molecular Formula
C13H13NO5
Molecular Weight
263.24899999999997 g/mol
SMILES
C1C(N(CC1=O)C(=O)OCC2=CC=CC=C2)C(=O)O
InChIKey
RPLLCMZOIFOBIF-NSHDSACASA-N
Last Updated: 2025-11-07 12:11
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